Houjun Liu

Immunogen Design

Using a bunch of signals to create a 3d representation of the system

features

  • cyro-EM
  • x-ray
  • tomo
  • glynomics/libidomics
  • genetics

studying large-scale viron behavior

Misc. Discoveries bydoing a bunch of MD

  • proteins of specific virons “breath”: oning and closing an entire backbone group; this is not yet quantified in physical modeling
  • when its open, the “breathing open” motion causes the virus to be vunerable
  • *we don’t *
  • “we are so biased by what we can see experimentally”