changes to central dogma
Last edited: August 8, 2025- 80% of the human genome is actually transcribed
- very little “junk DNA”
- 40% IncRNA are gene specific
characteristic polynomial
Last edited: August 8, 2025The polynomial given by the determinant of:
\begin{equation} det(A-\lambda I) \end{equation}
for some Linear Map \(A\). Solutions for \(\lambda\) are the eigenvalues. This is because something is an eigenvalue IFF \((A-\lambda I)v = 0\) for some \(\lambda, v\), so we need \((A-\lambda I)\) to be singular.
Characteristic polynomial of a 2x2 matrix is given by \(\lambda^{2}-tr(A)\lambda + det(A)\).
charged
Last edited: August 8, 2025an atom is said to be charged when there is an imbalance between its number of protons and electrons.
additional information
units of charge
charge is measured in SI unit \(C\), coulomb. However, we are often dealing with \(e\), the charge of an electron (as ultimate that’s the principle way by which charge moves around). \(e \approx 1.6 \times 10^{-19} C\).
net charge can be neither created nor destroyed
Unsurprisingly, though you can move electrons around, they will be conserved across a system.
Chatbot
Last edited: August 8, 2025Two main Dialogue Systems architectures:
- frame based systems: talk to users + accomplish specific tasks
- LLM: reasoning as agents
Dialogue Systems vs Chatbot
Previously, when we say Chatbot we mean task-based systems
humans and chat
humans tend to think of Dialogue Systems as human-like even if they know its not. this makes users more prone to share private information and worry less about its disclosure.
ELIZA
see ELIZA
LLM Chatbots
Training Corpus
C4: colossal clean crawled corpus

