to prove that something goes both ways: given \(A\Rightarrow B\), and \(A \Leftarrow B\), \(A \Leftrightarrow B\).

We really really want to prove:

\begin{equation} \text{BPP} \subseteq \text{P} \end{equation}

which will give \(\text{P} = \text{BPP}\).

How about we replace the truly random bits on the random tape \(r \in \qty {0,1}^{\text{poly}\qty(|x|)}\) with “pseudo-randomness” bits and prove that \(M\) can’t tell the difference.

Namely, a thing that is “pseudo-random” is easier to brute force over. So, we ideally can brute force over \(\text{poly}\qty(n)\) many outcomes instead of \(2^{\text{poly}\qty(n)}\) in the case of true randomness.

v-structure whose parents are unconnected are immoral

This is immoral:

This is moral

Using a bunch of signals to create a 3d representation of the system

features

• cyro-EM
• x-ray
• tomo
• glynomics/libidomics
• genetics

studying large-scale viron behavior

Misc. Discoveries bydoing a bunch of MD

• proteins of specific virons “breath”: oning and closing an entire backbone group; this is not yet quantified in physical modeling
• when its open, the “breathing open” motion causes the virus to be vunerable
• *we don’t *
• “we are so biased by what we can see experimentally”

Using a bunch of signals to create a 3d representation of the system

features

• cyro-EM
• x-ray
• tomo
• glynomics/libidomics
• genetics

studying large-scale viron surface protein behavior using MD

“we are so biased by what we can see experimentally, so do MD”

“breathing” motion

• proteins of specific virons “breath”: oning and closing an entire backbone group; this is not yet quantified in physical modeling
• when its open, the “breathing open” motion causes the virus to be vunerable
• so some antibodies jam into the open position

“head tilting” motion

• when its tilted, there is an epitope that becomes exposed
• this is a site that’s possible for introduction of what’s needed

overall architecture

• use conventional MD
• discover regions of instability (see above for examples) for possible binding surfaces
• bam inhibition!

maybe at some point run a cyro-EM to experimentally run some